Image 1 | Machine learning augmented single-cell omic analysis reveals the molecular landscapes of human hippocampal immature neurons across the lifespan--Center for Excellence in Brain Science and Intelligence Technology

Image 1 | Machine learning augmented single-cell omic analysis reveals the molecular landscapes of human hippocampal immature neurons across the lifespan

Time：2024-05-14

(Upper panel) We have developed a machine learning-driven single-cell RNA sequencing analysis to reveal the molecular characteristics of human hippocampal immature neurons across the lifespan and in Alzheimer’s disease. (Lower panel) We revealed newborn immature neurons arising from adult neurogenesis in the human hippocampus using immunohistology. Figure revised from: (1) Nature 2022, PMID: 35794479, https://doi.org/10.1038/s41586-022-04912-w; (2) Nature Neuroscience 2025, PMID: 40790267, https://doi.org/10.1038/s41593-025-02027-9.

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