A joint research team led by Dr. LIU Jingyu and Dr. ZHU Shujia from the CEBSIT, has revealed that missense mutations in PiT2-loop7 cause inorganic phosphate (Pi) dyshomeostasis by affecting the phosphorylation-regulated cell-surface localization of PiT2, which finally leads to primary familial brain calcification (PFBC).
A joint research team led by Dr. XU Huatai from the CEBSIT, has demonstrated the unique design of the neural microcircuit in the ventromedial hypothalamus (VMH).
Chinese researchers have reconstructed the whole-brain projection atlas of 6,357 single neurons in the prefrontal cortex of a mouse brain and established the world's largest database for mouse single-neuron projectome.
Shanghai scientists have found in lab tests that a novel gene editing approach could for the first time regenerate retinal ganglion cells and therefore restore sight of mice that suffer from permanent visual impairment.